Piracetam is one of most popular and commonly used nootropic drugs on the market. It has been used by millions of individuals worldwide and continues to be used as a prescription drug in many countries because of the positive impacts it can provide for patients who struggle with memory problems.

In the early 1970s, piracetam was discovered by a Romanian scientist as a synthetic derivative of the neurotransmitter GABA. For whatever reason, this derivative works wonders for people with memory loss and even improves the memory of ordinary students and high performance individuals of all ages.

There is some controversy about the discovery of piracetam. Some claim that piracetam was discovered even early in 1964 by a Belgian team of scientists, but either way this is the drug that was used to coin the term “nootropic”.

Over the last 40 years there have been dozens of clinical trials on both animals and humans. The human trials have shown tremendous results, which is why so many countries still use piracetam as a prescription drug for Alzheimer’s and senile dementia to this day. The name of piracetam varies widely by country as well. For example, some other common names include cerebrospan, nootron, nootropil, and nootropyl.

How Does Piracetam Work?

Piracetam is a mystery in some senses because everything about the drug and how it interacts with the brain is not yet known. What is known looks incredibly promising. One way that piracetam helps to improve brain health is by improving the permeability of cell membranes. This allows the dispersal of oxygen to each of the cells in the brain. This increased oxygenation creates a number of advantages for the human brain. If you consider what happens when you don’t have enough oxygen to breath, you will see why it is so important for the brain to get enough.

Another way that piracetam helps to improve your cognition is through the neuroprotective enhancement of neurons and synapses. The circulation and blood flow is enhanced, which helps to bring nutrients more effectively and obviously gives the best results for anyone who is struggling with poor blood flow.

Finally, there is a lot of discussion of how piracetam can improve your acetylcholine uptake and utilization. Most of the time, your brain tries to soak up acetylcholine (an essential neurotransmitter required for memory formation), but piracetam can help it to do it better and in the specific parts of the brain that are useful for memory formation.

There are other theories about how piracetam can be useful for improving your cognitive abilities as well. The science of it can be complicated, but it might be useful to know. For example, piracetam usage can increase cAMP, which stands for cyclic adenosine monophosphate, which improves mitochondrial function. As early as 1993 reports showed that piracetam was useful for NMDA receptors and stimulating the growth of neurological connections.

Piracetam Benefits

Before you become too interested in any nootropic, it is important to first understand the benefits that you might witness as a result of using the drug. The piracetam benefits are manifold and depend highly on the person, but it is important for you to first get the basics.

Memory formation and learning – The reason piracetam is used across the globe is because of the memory formation benefits. For most people who are aging, creating new memories and maintaining the old ones can be very difficult. This is where piracetam is helpful, but it can also be useful for people who are not old as well. Younger individuals can utilize piracetam in order to improve their memory for school or other tasks.

The great thing about piracetam is that it has so many studies to back up the claims. Because it has been around for around 40 years, there are plenty of studies that show how daily doses of piracetam can cause improvements in working memory and recall. Through the various testing, it is obvious that piracetam works well for people of all ages.

Concentration and focus – Some people also notice that piracetam can be effective for improving their ability to concentrate and focus on specific tasks. For example, piracetam offers increased blood flow and oxygen to the brain, which are both useful for the purpose of improving concentration and focus.

For anyone who is tired of caffeine or other stimulants, using piracetam is a useful way of replacing them in a safer and healthier way.

Mood enhancement – A lot of people witness great improvements in their mood as a result of taking piracetam. For whatever reason, this is a great nootropic that improves mood through specific neurotransmitter details that are largely unknown to many scientists and researchers. The additional dopamine modulation may have something to do with the mood, but again it might also be due to better blood flow.

Piracetam for Elderly and Young – The great thing about the benefits of piracetam is that it might be different for each person and age group, but it is still helpful. Almost everyone will see a benefit from using piracetam at some point in their life and it is important to see how it can be used for each stage.

Elderly patients who struggle with memory loss, injury to the head, or Parkinson’s disease / Alzheimer’s might find that using piracetam is one of the best things that they can do. In most cases, it is a great way of improving overall memory.

Piracetam Side Effects

Before taking any nootropic, it is a good idea to research and understand the side effects. Piracetam side effects are very well studied compared to other nootropics and supplements, which makes it a lot safer to take. Piracetam is non-toxic in the body within a recommended dose and even what are considered “mega doses”. While it is not recommended to take mega doses, the studies on piracetam show that there is relatively little to fear in taking too much of the compound

Piracetam and other nootropics are studied using a term called the LD50. This is the dose that is lethal to 50% of the population. In reports of taking 8 grams or more of piracetam there are no adverse effects according to the studies. Most of the time, this is not the case and you must be careful with the dosage. For some reason, racetams are relatively safe in almost all circumstances.

The common side effects of piracetam that are reported relate to headaches, which are usually easily remedied with the right supplementation. Some mild headaches and jaw pain can be attributed to a lack of choline the diet. This lack of choline results in a lack of acetylcholine and usually this can create major problems for the use of piracetam. When piracetam is used, the hippocampus will try to increase the utilization and uptake of acetylcholine, which means you might need to supplement with choline to have enough.

Other people have the opposite problem. If they take high doses of choline they will have headaches or similar symptoms as well. It is important for you to make sure that you are not continuing to use the drug if you are seeing any of these side effects. While you can test with yourself to see whether it is the dosage, you do not want to continue taking it just for the mental enhancement aspect.

Drug Interactions of Piracetam

Sometimes you will have interactions with your nootropic drugs and the other substances in your daily life. For some of these, it can be quite dangerous so you want to make sure not to combine them. A lot of people that have a history of narcotics or drug use should consult a professional before trying to use specific types of nootropics like piracetam.

Alcohol – Even though some people on communities like Longecity and Reddit claim to like the effect of piracetam and alcohol, it is important to know that it can lead to alcohol poisoning. Piracetam can impair the perception of intoxication, which makes it easier to have poor motor skills and get hurt.

Amphetamines – Drugs like Adderall and just regular amphetamines found on the streets are enhanced with the use of piracetam. If you are using any kind of amphetamine, it might not be a good idea to use piracetam or any of the analogues.

Piracetam Dosage

Getting the right dosage for your particular biochemistry is the most important thing, but that doesn’t mean that you cannot take general guidelines when you are starting out. The low dose as recorded by Reddit and Longecity is around 400 – 800 mg per serving. Some people take this once and others decide to take it 2 or 3 times in a day.

Like creatine, there is some level of accumulation when it comes to piracetam. This might mean that you take a “mega dose” or “attack dose” for a period of a week. This might include up to 3200 mg depending on your size and what type of results you are looking for. If you want to stay on the safe side, you can start off with 1600 mg per day.

Reddit very clearly states that 1600 mg three times a day is a good place to start and they even say that 6400 mg per day is useful. This should be your target even if you do not start off here. You may not feel a lot of advantages at a lower level and this is why you can slowly and incrementally improve the levels to a higher one.

Nootropic Stacks with Piracetam

There is a common trend in the nootropics community to create what are called “nootropic stacks”. These stacks are useful for people who are trying to improve their cognition and get the best results possible from their brain. This often includes putting complimentary nootropics together in order to get the maximum results.

Piracetam and Choline

This is one of the most common combinations that involves piracetam and it is usually the place where people start. It is important for you to start here if you want to take the most advantage of the learning and memory benefits that come with piracetam. Even though there are plenty of different drugs that can improve memory, this combination could be the most useful for beginners.

Piracetam, Choline, and Other Racetams

There are a lot of different racetams within the family that are similar to piracetam, but just different enough that it is worth it to take both. Some of these include aniracetam, oxiracetam, and even things like phenylpiracetam. Combining all of these with choline can give you memory and stimulatory advantages that you can’t find elsewhere.

Piracetam, Choline + Caffeine, L-Theanine

Even though piracetam and choline are well studied for memory and learning, they do not help as much as some people would like for concentration and focus. For that, it might be a good idea to add caffeine and L-theanine in a 1:2 ratio. This combination is going to yield the best results for all the different aspects you are going for.

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Author: Racetam.Org Team

We are daily users of nootropics interested in educating the public about racetams, a specific family of nootropics, that has many studies documenting the efficacy of racetams and virtual lack of adverse side effects.

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